The international break always brings fresh worries over potential injuries for clubs - and managers - and it's no different at Tottenham Hotspur.
Thomas Frank will be watching his players involved in international matches carefully and some of his fears may have been realised over the weekend.
Making his way back from injury that has kept him out so far this season, it seems that Yves Bissouma has now suffered another problem while representing Mali.
- Tottenham are two games away from Cristian Romero nightmare scenario
- Behind-closed-doors Tottenham friendly and Thomas Frank's five big positives from the break
In a more positive light, though, the international breaks also provide players making their way back from injury extra-time to step up their recovery ahead of the return of Premier League fixtures.
With that in mind, here's the latest news from the Spurs injury room ahead of their Premier League clash against Aston Villa this weekend;
Yves BissoumaInjury: Ankle
The midfielder made his return to action for Mali in their World Cup Qualifier on Sunday night. However, his match ended early when he suffered the injury.
Bissouma showed he was in a lot of pain - and he was eventually stretchered off the pitch. It comes after he made a return from a knee injury.
Spurs now face a wait to discover the extent of the injury.
Potential return date: TBC
Dominic SolankeInjury: Ankle
What Frank has said: "Dominic has had a minor procedure, and it went well. As I said in Bodo, in terms of a time frame, we'll know more after the international break."
Potential return date: TBC
Randal Kolo MuaniInjury: Dead leg
What Frank has said: "Kolo Muani has been back on the pitch for the last two days, so that's very positive."
The forward played for 45 minutes in the behind-closed-doors friendly against Watford on Friday.
Predicted return date: October 19 vs Aston Villa (H)
Dejan KulusevskiInjury: Knee
What Frank has said: "He's a key, key player for us. Instead of putting an exact month on [his return]. I just want him back as quick as possible. I know the medical team and Dejan are working very hard on that. It's not tomorrow, hopefully not too far away."
Potential return date: January 2026
Kota TakaiInjury: Plantar Fascia
What Frank has said: "Kota is better and better. He has trained fully with the team for a week to 10 days."
Predicted return date: October 19 vs Aston Villa (H)
Radu DragusinInjury: Knee
What Frank has said: "He's progressing well. He's been on the grass for three weeks - and is progressing as well as it should. We all know coming back from an ACL is a long one - he's on track - but it will be a few weeks before he's able to be involved."
Potential return date: November 2025
James MaddisonInjury: Knee
The attacking midfielder suffered an anterior cruciate ligament rupture during pre-season that will effectively rule him out for the season. As he continues his recovery, Maddison is regularly sharing updates - in his YouTube series.
Potential return date: TBC
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